What medical consequences can a fire have on occupants? Fires break out for all kinds of reasons. Unattended candles, faulty electrical wiring or a person who falls asleep while smoking a cigarette could all lead to a conflagration that causes both property damage and injury to the occupants of the domicile. People who live through a building fire can experience a number of serious medical consequences as a result. Knowing three of the most common medical consequences of a significant fire can help you recognize the signs of these issues and seek the right care after a house fire.